• Tube of Stratum Nightly Active face cream on a blue background.
  • A close-up of a creamy beige lotion being scooped by a fingertip.
  • Close-up of a person's face with cream being applied to the skin.
  • Close-up of a person's face with a skincare product applied on their cheek.

Made by Dr. Syed

Stratum Nightly Active

NanoActive Retinaldehyde 0.1% Cream (30g)

Price: $38.00

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We took the strongest over the counter retinoid (retinal) and combined it with moisturizing and soothing ingredients to reduce irritation. Formulated, tested and approved by dermatologist Dr. Usama Syed.

How does it help your skin?

Ingredients

Directions for Use

How long before I see results?

Warnings

What Makes Stratum Nightly Active Special?

Dr. Usama Syed
Board-Certified Dermatologist
Co-Founder & CEO, Stratum

Featured reviews

Real results from people like you

These customers’ results have not been independently verified. Individual results will vary.

Flowchart illustrating the conversion: retinol to retinal to retinoic acid.

The Science

Why retinal, not retinol?

Retinoids are a group of compounds derived from vitamin A. These include retinol, retinal, and retinoic acid (prescription-only). Most over-the-counter skincare products use retinol. However, retinol needs two steps to convert into the active form, making it less potent. Retinal needs just one conversion step, making it more effective but with less irritation than retinoic acid.

How to use Nightly Active in your routine

Close-up of a finger covered in a bubbly liquid.

1. Cleanse your face

Ideally, you start your night time routine with a round of cleansing. This can be a hydrating or foaming cleanser depending on your skin type.

Close-up of smooth, white cream in a circular container.

2. Apply a moisturizer (optional)

Usually with retinoids, this step isn't optional. With Nightly Active, we already pack in moisturizing ingredients, so it's up to you if you need extra.

Close-up of fingers applying cream on a person's cheek.

3. Apply Nightly Active

Take a pea-sized amount and apply it across your face. Avoid the area immediately beneath the eyes (retinal can cause dry eyes).

94%

Had skin improvement

Over 94% of users of retinal based skincare products noticed improvement in their skin appearance after 8 weeks.*

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* Results vary. Data taken from peer-reviewed scientific literature. 

Frequently asked questions

Can I use Nightly Active with other skincare products?

What should I expect when I first start using Nightly Active?

Does retinal make me more sensitive to the sun?

Can I use this product for my undereyes?

Is it normal to experience peeling with Nightly Active?

Is Nightly Active fragrance-free?

Can I use Nightly Active on my neck?

How do I know if Nightly Active is working for me?

Will I get purging from Nightly Active?

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Still not sure?
Email the founder.

Stratum's Nightly Active was formulated, tested, and approved by Dr. Usama Syed, a board-certified dermatologist from New York. If you have any follow up questions about the product before purchase, you can message him directly using drsyed@heystratum.com.

This page has been medically reviewed by Dr. Usama Syed, MD, FAAD, a board-certified dermatologist. This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease. Formulated and filled in USA. Distributed by Stratum Global, LLC Brooklyn, NY 11201